HUANG Zhiwei, Ph.D. Assistant Professor
	Division of Bioengineering Faculty of Engineering 9 Engineering Drive 1 Singapore 117576 biehzw@nus.edu.sg Office: Block E2-02-30 Tel: +(65) 6516-8856 Fax: +(65) 6872-3069 Huang’s group: http://www.bioeng.nus.edu.sg/optbioimaging/huang/
Courses taught: BN3401 Biomedical Electronics and Systems BN4406 Biophotonics and Bioimaging GEK2505 Introductory Biomedical Engineering BN5207 Medical Imaging Systems
Research Interests/Areas 1. Biospectroscopy and Endoscopic Imaging 2. Coherent Anti-Stokes Raman Scattering Microscopy 3. Near-field Optical Microscopy 4. Single Molecule Imaging and Fluorescence Lifetime Imaging 5. Laser Interactions with Tissue and Cells
Selected Publications J Mo, W Zheng, Jeffrey Low, J Ng, A Ilanacheran, Z Huang, High wavenumber Raman spectroscopy for in vivo detection of cervical dysplasia, Analytical Chemistry, 81, 8908-8915 (2009). J Lin, F Lu, H Wang, W Zheng, C Sheppard, Z Huang, Improved contrast radially polarized coherent anti-Stokes Raman scattering microscopy using annular aperture detection, Applied Physics Letters, Vol. 95, No. 13, 133703 (2009). SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang, Near-infrared Raman spectroscopy for optical diagnosis in the stomach: Identification of Helicobacter-pylori infection and intestinal metaplasia, Int. J. Cancer, 10.1002/ijc.24935, in press (2009). SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang, Near-infrared Raman spectroscopy for early diagnosis and typing of adenocarcinoma in the stomach, British Journal of Surgery, accepted (2009). C Yuen, W Zheng, Z Huang, Optimization of extinction efficiency of gold-coated polystyrene beads substrates improves surface-enhanced Raman scattering effects by post-growth microwave heating treatment, J. Raman Spectroscopy, DOI 10.1002/jrs.2464, in press (2009). F Lu, W Zheng, Z Huang, Coherent anti-Stokes Raman scattering microscopy using tightly focused radially polarized light, Optics Letters, Vol.34, No.12, 1870-1872 (2009). Z Huang, SK Teh, W Zheng, J Mo, K Lin, X Shao, KY Ho, M Teh, KG Yeoh, Integrated Raman spectroscopy and trimodal wide-field imaging techniques for real-time in vivo tissue Raman measurements at endoscopy, Optics Letters, Vol.34, No.6, 758-760 (2009). J Lin, H Wang, W Zheng, F Lu, C Sheppard, Z Huang, Numerical study of effects of light polarization, scatterer sizes and orientations on near-field coherent anti-Stokes Raman scattering microscopy, Optics Express, 17 (4), 2423-2434 (2009). SK Teh, W Zheng, David P Lau, Z Huang, Spectroscopic diagnosis of laryngeal carcinoma using near-infrared Raman spectroscopy and random recursive partitioning ensemble techniques, Analyst, 134, 1232-1239 (2009). SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang, Near-infrared Raman spectroscopy for gastric precancer diagnosis, J. Raman Spectroscopy, 40, 908-914 (2009). F Lu, W Zheng, Z Huang, Elliptically polarized coherent anti-Stokes Raman scattering microscopy, Optics Letters, 33 (23), 2842-2844 (2008). F Lu, W Zheng, Z Huang, Phase-controlled polarization coherent anti-Stokes Raman scattering microscopy for high sensitive and high contrast molecular imaging, Journal of the Optical Society of America B, 25 (11), 1907-1913 (2008). C Yuen, W Zheng, Z Huang, Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with post-growth microwave treatment, Journal of Biomedical Optics, 13 (6), 064040 (2008). C Yuen, W Zheng, and Z Huang, Surface-enhanced Raman scattering: principles, nanostructures, fabrications and biomedical applications, J. Innovative Optical Health Sciences (JIOHS), 1 (2), 267-284 (2008). F. Jaillon, W. Zheng, and Z. Huang, Half-ball lens couples a beveled fiber probe for depth-resolved spectroscopy: Monte Carlo simulations, Appl. Opt. 47, 3152-3157 (2008). F Lu, W Zheng, and Z Huang, Heterodyne polarization coherent anti-Stokes Raman scattering microscopy, Applied Physics Letters, 92 (12), 123901 (2008). F Lu, W Zheng, C Sheppard, Z Huang, Interferometric polarization coherent anti-Stokes Raman scattering microscopy, Optics Letters, 33(6), 602-604 (2008). F Jaillon W Zheng, Z Huang, Beveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo Simulations, Phys. Med. Biol. 53, 937-951 (2008). SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang, Diagnostic potential of near-infrared Raman spectroscopy in the stomach: differentiating dysplasia from normal tissue. British Journal of Cancer, 98, 457-465 (2008). SK Teh, W Zheng, KY Ho, M Teh, KG Yeoh, Z Huang, Diagnosis of gastric cancer using near-infrared Raman spectroscopy and classification and regression tree techniques, Journal of Biomedical Optics, 13 (3), 034013 (2008). E Widjaja, W Zheng and Z Huang, Classification of colonic tissues using near-infrared Raman spectroscopy and support vector machines. Int. J. Oncology, 32: 653-662 (2008).