Anqi QIU, Ph.D.

Assistant Professor

Division of Bioengineering

Faculty of Engineering

National University of Singapore

 

Visiting Professor

Center for Imaging Science

The Johns Hopkins University

 

Contact:

Email: bieqa@nus.edu.sg

Office: E1-08-14

Tel:  +(65) 6516 7002

Fax: +(65) 6872 3069

 

Computational Functional Anatomy Laboratory Web: http://www.bioeng.nus.edu.sg/cfa

 

Educations:

2006         Ph.D. in Electrical and Computer Engineering             Johns Hopkins University

2005         M.S. in Applied Mathematics and Statistics                Johns Hopkins University

2002         M.S. in Biomedical Engineering                                 University of Connecticut

1999         B.S. in Biomedical Engineering                                  Tsinghua University

 

Research Interests:

Computational Functional Anatomy (CFA) is a new discipline in the medical image analysis that mathematically models the anatomy and functions of organs using multi-modality images. It aims at studying both anatomical and functional information in the structures of anatomical coordinates for identifying image biomarkers associated with diseases. It includes the following five areas:

1)       Construction of anatomical manifolds, such as points, curves, surfaces, subvolumes (image segmentation, feature extraction);

2)       Construction of anatomical association (registration);

3)       Extraction of morphometric and functional measurements (modeling);

4)       Signal processing in anatomical manifolds (signal modeling, signal processing);

5)       Statistical inference on anatomy and functions in the anatomical cooridinates (random fields, pattern recognition).

Please visit http://www.bioeng.nus.edu.sg/cfa for details.

 

Publications:

JOURNAL PAPERS

1.         Anqi Qiu, Deana Crocetti, Marcy Adler, Mark Mahone, Martha Deckla, Michael I. Miller, and Stewart H. Mostofsy, “Basal ganglia volume and shape in children with ADHD”, Am J Psychiatry, accepted.

2.         Anqi Qiu, Michael I. Miller, “Multi-Structure Network Shape Analysis via Normal Surface Momentum Maps”, NeuroImage, accepted.

3.         Joan Glaunès, Anqi Qiu, Michael I. Miller, Laurent Younes, “Large Deformation Diffeomorphic Curve Matching”, International Journal of Computer Vision, (equal contribution with the first author, correspondence author), accepted.

4.         Anqi Qiu, Marc Vaillant, Patrick Barta, J. Tilak Ratnanather, Michael I. Miller, "Region of Interest Based Analysis of Cortical Thickness Variation of Left Planum Temporale in Schizophrenia and Psychotic Bipolar Disorder", Human Brain Mapping, 29(8):973-985, 2008. (COVER PAGE)

5.         Michael I. Miller, Carey Priebe, Anqi Qiu, Bruce Fischl, Anthony Kolasny, Youngser Park, Evelina Busa, Jorge Jovicich, Peng Yu, Brad Dickerson, Randy L. Buckner, and the Morphometry BIRN, “Collaborative Computational Anatomy: the Perfect Storm for MRI Morphometry Study of the Human Brain via Diffeomorphic Metric Mapping”, Human Brain Mapping, accepted.

6.         Hao Huang, Can Ceritoglu, Xin Li, Anqi Qiu, Michael I. Miller, Peter C.M. van Zijl, Susumu Mori, “Correction of B0-Susceptibility Distortion in SENSE Single-shot EPI-based Diffusion Weighed Images Using Large Deformation Diffeomorphic Metric Mapping”, Magnetic Resonance Imaging, accepted.

7.         Anqi Qiu, Laurent Younes, Michael I. Miller, “Intrinsic and Extrinsic Analysis in Computational Anatomy”, NeuroImage, 39(4):1803-1814, 2008. (COVER PAGE)

8.         Laurent Younes, Anqi Qiu, Raimond L. Winslow, Michael I. Miller, “Transport of Relational Structures in Groups of Diffeomorphisms”, Journal of Mathematical Imaging and Vision, 32:41-56,2008.

9.         Anqi Qiu, Laurent Younes, Michael I. Miller, John G. Csernansky, “Parallel Transport in Diffeomorphisms Distinguishes Time-Dependent Hippocampal Surface Atrophy in Healthy Aging and Alzheimer’s Disease”, NeuroImage, 40(1):68-76, 2008.

10.     Anqi Qiu, Laurent Younes, Lei Wang, J. Tilak Ratnanather, Sarah K. Gillepsie, Gillian Kaplan, John Csernansky, Michael I. Miller, “Combining Anatomical Manifold Information via Diffeomorphic Metric Mappings for Studying Cortical Thinning of the Cingulate Gyrus in Schizophrenia”, Neuroimage, 37, 821-833, 2007. (COVER PAGE)

11.     Lei Wang, Malini Hosakere, Joshua C. L. Trein, J. Tilak Ratnanather, Deanna M. Barch, Paul A. Thompson, Anqi Qiu, Mokhtar Gado, Michael I. Miller, John G. Csernansky, “Abnormalities of Cingulate Gyrus Neuroanatomy in Schizophrenia”, Schizophr Res 93, 66-78, 2007.

12.     Marc Vaillant, Anqi Qiu, Joan Glaunès, Michael I. Miller, “Diffeomorphic Metric Surface Mapping in Subregion of the Superior Temporal Gyrus”, NeuroImage 34, 1149-1159, 2007. (correspondence author).

13.     Anqi Qiu, Dmitri Bitouk, Michael I. Miller, “Smooth Functional and Structural Maps on the Neocortex via Orthonormal Bases of the Laplace-Beltrami Operator”, IEEE Trans. Med. Imaging, 25, 1296-1306, 2006.

14.     Anqi Qiu, Benjamin J. Rosenau, Adam S. Greenberg, Patrick Barta, Steven Yantis, Michael I. Miller, "Estimating Linear Cortical Magnification in Human Primary Visual Cortex via Dynamic Programming", NeuroImage, 31(1), 125-138, 2006.

15.     Patrick Barta, Michael I. Miller and Anqi Qiu, “A Stochastic Model for Studying the Laminar Structure of Cortex from MRI”, IEEE Trans. Med. Imaging, 24 (6), 728-743, 2005.

16.     Anqi Qiu, Christoph E. Schreiner and Monty A. Escabi, "Gabor Analysis of Auditory Midbrain Receptive Fields: Spectro-Temporal and Binaural Composition”. J Neurophysiol, 90, 456-476, 2003.

17.     Anqi Qiu and Jing Bai, "Multiple Modeling in the Study of Interaction of Hemodynamics and Gas Exchange", Computers in Biology and Medicine, 31, 59-72, 2001

18.     Anqi Qiu and Jing Bai, "A Mathematical Model of Human Respiratory System", Beijing Biomedical Engineering, No. 3, 2000.

 

CONFERENCE PROCEEDINGS

1.         Moo K. Chung, Anqi Qiu, Brendon, M. Nacewicz, Seth Pollak, Richard J. Davidson, “Tiling Manifolds with Orthonormal Basis”, MICCAI2008, workshop on MFCA, Sep. 2008, New York (oral presentation).

2.         Anqi Qiu, Michael I. Miller, “Cortical Hemisphere Registration via Diffeomorphic Curve Mapping”, MICCAI, 10:186-193, Oct 2007, Australia.

3.         Anqi Qiu, Benjamin J. Rosenau, Adam S. Greenberg, Patrick Barta, Steven Yantis, Michael I. Miller, "Localizing Retinotopic fMRI Activation in Human Primary Visual Cortex via Dynamic Programming", Proceedings of the 27nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Sep 2005, Shanghai.

4.         Anqi Qiu, Jing Bai, “Interaction of hemodynamics and gas exchange: a computer simulation”, Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 3:1923 – 1926, Jul 2000, Chicago.

 

ABSTRACTS

  1. Jidan Zhong, Randy L. Buckner, Bruce Fischl, Michael I. Miller, Anqi Qiu, “Differences in Corpus Callosum Area and Shape in Advanced Aging and Alzheimer’s Diesease”, Human Brain Mapping, Jun 2008, Australia.
  2. Anqi Qiu, Michael I. Miller, “Subcortical Network Shape Analysis via Segmentation Denoising and Random Surface Momentum Maps”, Human Brain Mapping, Jun 2008, Australia.
  3. Anqi Qiu, Timothy Brown, Bruce Fischl, Anthony Kolasny, Jun Ma, Randy L. Buckner, Michael I. Miller, “Subcortical Structure Template Generation with its Applications in Shape Analysis”, Human Brain Mapping, Jun 2008, Australia.
  4. Deana Crocetti, Anqi Qiu, Marcy Adler, Michael I. Miller, and Stewart H. Mostofsky, “Analysis of Basal Ganglia Morphometry in Autism Using Large Deformation Diffeomorphic Metric Mapping (LDDMM)”, May 2008, London.
  5. Anqi Qiu, Michael I. Miller, “Computational Functional Anatomy”, Asilomar Conference on Signals, Systems, and Computers, Nov 2007, Montery, CA.
  6. Anqi Qiu, Laurent Younes, Michael I. Miller, “Intrinsic and Extrinsic Analysis in Computational Anatomy”, Human Brain Mapping, Jun 2007, Chicago.
  7. Anqi Qiu, Laurent Younes, Lei Wang, J. Tilak Ratnanather, John Csernansky, Michael I. Miller, “Cortical Thinning of Cingulate Gyrus in Schizophrenia”, International Congress on Schizophrenia Research, Apr 2007, Colorado Springs.
  8. Marc Vaillant, Anqi Qiu, Michael I. Miller, “Curve and Surface Matching via Currents”, SIAM, Jul 2006, Boston.
  9. Anqi Qiu, Dmitri Bitouk, Michael I. Miller, “Smooth Anatomical and Functional Maps via Harmonics of Cortical Surface”, Human Brain Mapping, Jun 2006, Florence.
  10. Anqi Qiu, Marc Vaillant, Patrick Barta, Michael I. Miller, J. Tilak Ratnanather, “Left Planum Temporale Cortical Thickness Variation in Schizophrenia”, Human Brain Mapping, Jun 2006, Florence.
  11. Marc Vaillant, Anqi Qiu, Joan Glaunes, J. Tilak Ratnanather, Michael I. Miller, “Validation of Cortical Surface Matching via Currents”, Human Brain Mapping, Jun 2006, Florence .
  12. Anqi Qiu, Patrick Barta,, Michael I. Miller, J. Tilak Ratnanather,  “Asymmetry in Laminar Structure of Planum Temporale”, the 29th Annual Midwinter Meeting, Association for Research in Otolaryngology, Feb 2006, Baltimore.
  13. Anqi Qiu, Dmitri Bitouk, J Tilak Ratnanather, Clare Poynton, Lei Wang, Dana Boatman, Patrick Barta, John Csernansky, Michael I. Miller, “Visualizing cortical thickness on the gray/white cortical surface”, Human Brain Mapping, Jun 2005, Toronto.
  14. Anqi Qiu, Benjamin J. Rosenau, Adam Greenberg, Steven Yantis, Patrick Barta, Michael I. Miller “Linear Cortical Magnification within Human Primary Visual Cortex via Dynamic Programming”, Human Brain Mapping, Jun 2005, Toronto.
  15. Benjamin J. Rosenau, Adam S. Greenberg, Janet S. Sunness, Anqi Qiu, Patrick Barta, Michael I. Miller, Steven Yantis, “Retinal Lesion Projection Zones Identified in Visual Cortex Using fMRI”, Human Brain Mapping, Jun 2005, Toronto.
  16. Anqi Qiu, Dmitri Bitouk, Lei Wang, J Tilak Ratnanather, John G. Csernansky, Michael I. Miller, "Cingulate Cortical Thickness Variability on the Gray/White surface", International Congress on Schizophrenia Research, Apr 2005, Savannah, GA.
  17. Anqi Qiu, Patrick Barta, Michael I. Miller, “A parametric statistical model for measuring cortical thickness.” Human Brain Mapping, Jun 2004, Budapest.
  18. Monty A. Escabi, Anqi Qiu, Heather L. Read, Christoph E. Schreiner, "Quantification of Spectrotemporal and Binaural Receptive Field Characteristics in the Cat Inferior Colliculus", the 32th Annual Meeting, Society of Neuroscience, Nov 2002, Orlando..
  19. Anqi Qiu, Monty A. Escabi, "Modeling spectrotemporal integration in the central nucleus of the inferior colliculus", the 25th Annual Midwinter Meeting, Association for Research in Otolaryngology, Jan 2002. St. Petersburg Beach.
  20. Anqi Qiu and Jing Bai, "A mathematical model of metabolic rate of oxygen in the human", Academic periodical abstracts of China, 2000, Beijing.

 

PATENTS

  1. Laurent Younes, Michael I. Miller, Anqi Qiu, “Renormalization of longitudinal or grouped anatomical data via parallel translation in shape manifolds”, US patent, pending.
  2. Susumu Mori, Michael I. Miller, Anqi Qiu, Can Ceritoglu, Jiangyang Zhang, “Description of Invention: Advanced Cost Functions for Image Registration for Automated Image Analysis: Multi-Channel, Hypertemplate and Atlases With Built-in Anatomical Variability”, US patent, pending.
  3. Susumu Mori, Michael I. Miller, Anqi Qiu, “Automated Surface-based Anatomical Analysis Based on Atlas-Based Segmentation of Medical Imaging”, US patent, pending.