Publications

Highly cited/Most accessed articles

18. Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells
Majid, E W, G Guan, B L Khoo, C L Wong, A A S Bhagat, P K Chaudhuri, D S W Tan, W T Lim, S C Lee, P C Y Chen, C T Lim*, J Y Han*, Lab on a Chip, 14, 1, 128-137, 2014. (*co-corresponding authors)Abstract

17. Isolation and retrieval of circulating tumor cells using centrifugal forces
Hou, H W, M E Warkiani, B L Khoo, Z R Li, R A Soo, D S W Tan, W T Lim, J Y Han, A A S Bhagat, C T Lim, Scientific Reports, 3, 1259, 2013.Article

16. Pinched flow coupled shear-modulated inertial microfludics for high-throughput rare blood cell separation
Bhagat, A A S, H W Hou, L D Li, C T Lim, J Y Han, Lab on a Chip, 11, 11, 1870-1878, 2011.Abstract

15. Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide
Lee, W C, C Lim, H Shi, L A L Tang, Y Wang, C T Lim, K P Loh, ACS Nano, 5, 9, 7334-7341, 2011.Abstract

14. Graphene-polymer nanofiber membrane for ultrafast photonics
Bao, Q L, H Zhang, J X Yang, S A Wang, D Y Tong, R Jose, S Ramakrishna, C T Lim, A P Loh, Advanced Functional Materials, 20, 5, 782-791, 2010.Abstract

13. Microfluidics for cell separation
Bhagat, A A S, H Bow, H W Hou, S J Tan, C T Lim, Medical & Biological Engineering & Computing, 48, 10, 999-1014, 2010.Abstract

12. AFM indentation study of breast cancer cells
Li, Q S, G Y H Lee, C N Ong, C T Lim, Biochemical and Biophysical Research Communications, 374, 4, 609-13, 2008.Abstract

11. Electrospun biomimetic nanocomposite nanofibers of Hydroxyapatite/Chitosan for bone tissue engineering
Zhang, Y Z, J R Venugopal, A El-Turki, S Ramakrishna, C T Lim, B Su, Biomaterials, 29, 32, 4314-22, 2008.Abstract

10. Fabrication of NiO nanowall electrodes for high performance lithium ion battery
Varghese, B, M V Reddy, Z Yanwu, C S Lit, T C Hoong, G V S Rao, B V R Chowdari, A T S Wee, C T Lim, C H Sow, Chemistry of Materials, 20, 10, 3360-3367, 2008.Article

9. α-Fe2O3 nanoflakes as an anode material for Li-ion batteries
Reddy, M V, T Yu, C H Sow, Z X Shen, C T Lim, G V S Rao, B V R Chowdari, Advanced Functional Materials, 17, 15, 2792-2799, 2007.Abstract

8. Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution
Chong, E J, T T Phan, I J Lim, Y Z Zhang, B H Bay, S Ramakrishna, C T Lim, Acta Biomaterialia, 3, 3, 321-330, 2007.Abstract

7. Coaxial electrospinning of fitcBSA encapsulated PCL nanofibers for sustained release
Zhang, Y Z, X Wang, Y Feng, J Li, C T Lim , S Ramakrishna, Biomacromolecules, 7, 4, 1049-1057, 2006.Abstract

6. Crosslinking of the electrospun gelatin nanofibers
Zhang, Y Z, J Venugopal, Z M Huang, C T Lim, S Ramakrishna, Polymer, 47, 8, 2911-2917, 2006.Abstract

5. Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria
Suresh, S, J Spatz, J P Mills, A Mmicoulet, M Dao, C T Lim, M Beil, T Seufferlein, Acta Biomaterialia, 1, 1, 15-30, 2005.Abstract

4. Large-scale synthesis and field emission properties of vertically oriented CuO nanowire films
Zhu, Y W, T Yu, F C Cheong, X J Xu, C T Lim, V B C Tan, J T L Thong, C H Sow, Nanotechnology, 16, 88-92, 2005.Abstract

3. Recent development of polymer nanofibers for biomedical and biotechnological applications
Zhang, Y Z, C T Lim, S Ramakrishna, Z M Huang, Journal of Materials Science - Materials in Medicine, 16,10, 933-946, 2005.Abstract

2. Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds
Zhang, Y Z, H W Ouyang, C T Lim, S Ramakrishna, Z M Huang, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 72B, 1, 156-165, 2005.Abstract

1. Electrospinning and mechanical characterization of gelatin nanofiber
Huang, Z M, Y Z Zhang, S Ramakrishna, C T Lim, Polymer, 45, 15, 5361-5368, 2004.Abstract

5. Lim, C T, J C H Goh (eds), IFMBE Proceedings Series on 13th International Conference on Biomedical Engineering, vol. 23, 2303 pp. in 3 volumes, 2009.
(Top 25% most downloaded Springer eBook in 2012)Abstract

4. Pinched flow coupled shear modulated inertial microfluidics with application towards high throughput circulating tumor cell separation
Bhagat, A A S, H W Hou, L D Li, C T Lim, J Han, Lab on a Chip, 11, 1870-1878, 2011.Abstract

3. Atomic force microscopy study of the antimicrobial action of Sushi peptides on Gram negative bacteria
Li, A, P Y Lee, B Ho, J L Ding, C T Lim, BBA – Biomembranes, 1768, 3, 411-418, 2007.
(Top 50 most downloaded papers in BBA - Biomembranes for 2007)Abstract

2. Coaxial electrospinning of (Fluorescein Isothiocyanate-cconjugated bovine serum albumin)-encapsulated Poly(ε-caprolactone) nanofibers for sustained release.
Zhang, Y Z, X Wang, Y Feng, J Li, C T Lim, S Ramakrishna, Biomacromolecules, 7, 4, 1049-1057, 2006.Abstract
(ACS Publications Most Assessed Articles - Biomacromolecules)Read more

1. Size Selective Assembly of Colloidal Particles on Template by Directed Self Assembly Technique
Varghese, B, C C Fook, S Sindhu, T Yu, C T Lim, S Valiyaveettil, C H Sow, Langmuir, 22, 8248-8252, 2006.Abstract
(ACS Publications Most Assessed Articles - Langmuir)Read more

8. Evaluation of electrospun PCL/Gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution
Chong, E J, T T Phan, I J Lim, Y Z Zhang, B H Bay, S Ramakrishna, C T Lim, Acta Biomaterialia, 3, 321-320, 2007.Abstract
(Science Direct Top 25 - Acta Biomaterialia)Read more

7. Experimental techniques for single cell and single molecule biomechanics
Lim, C T, E H Zhou, A Li, S R K Vedula, H X Fu, Materials Science and Engineering: C, 26, 8, 1278-1288, 2006.Abstract
(Science Direct Top 25 - Materials Science and Engineering: C)Read more

6. Mechanical characterization of nanofibers – A review
Tan, E P S, C T Lim, Composites Science & Technology, 66, 9, 1102-1111, 2006.Abstract
(Science Direct Top 25 - Acta Biomaterialia)Read more
(Science Direct Top 25 of all engineering journals)Read more

5. Mechanical models for living cells - A review
Lim, C T, E H Zhou, S T Quek, Journal of Biomechanics, 39, 2, 195-216, 2006.Abstract
(Science Direct Top 25 - Journal of Biomechanics)Read more

4. Crosslinking of the electrospun gelatin nanofibers
Zhang, Y Z, J Venugopal, Z M Huang, C T Lim, S Ramakrishna, Polymer, 47, 8, 2911-2917, 2006.Abstract
(Science Direct Top 25 - Polymer)Read more

3. Encapsulation of self-assembled FePt magnetic nanoparticles in PCL nanofibers by coaxial electrospinning
Song, T, Y Z Zhang, T J Zhou, C T Lim, S Ramakrishna, B Liu, Chemical Physics Letters, 415, 4-6, 317-322, 2006.Abstract
(Science Direct Top 25 - Chemical Physics Letters)Read more

2. Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria
Suresh, S, J Spatz, J P Mills, A Micoulet, M Dao, C T Lim, M Beil, T Sefferlein, Acta Biomaterialia, 1, 1, 15-30, 2005.Abstract
(Science Direct Top 25 - Acta Biomaterialia)Read more

1. Electrospinning and mechanical characterization of gelatin nanofiber
Huang, Z M, Y Z Zhang, S Ramakrishna, C T Lim, Polymer, 45, 15, 5361-5368, 2004.Abstract
(Science Direct Top 25 - Polymer)Read more

About the MechanoBioEngineering Laboratory

We seek to address important scientific and biomedical problems using interdisciplinary approaches, develop innovative solutions and translate them for biological and healthcare applications. Our focused areas include mechanobiology of human diseases and development of mechanobiologically inspired platforms in microfluidics, tunable nanomaterials and wearable microdevices to better detect, diagnose and treat diseases. We have won numerous research awards and honors and have also spun out several startup companies to translate technologies from our lab to bedside and market. We are affiliated with the Mechanobiology Institute, Centre for Advanced 2D Materials and SMART.


Contact Us
MechBioEng Lab

E3, #05-16, 2 Engineering Drive 3
Dept of Biomedical Engineering
NUS, Singapore 117581
Tel: (65) 6516 6564
Fax: (65) 6773 2205