Microhemodynamics refers to the study of red blood cells flow in the microcirculation. Due to the close relationship between blood rheological properties and human cardiovascular diseases such as hypertension, atheroclerosis and stroke, our lab has carried out extensive and intensive research work on understanding the influence of altered blood rheological properties on important microcirculatory parameters seen in pathological conditions. In addition, we seek to develop novel measurement techniques to quantify blood rheological properties such as whole blood viscosity and red blood cell aggregation. Our ultimate engineering goal is to develop new clinical diagnostic devices for human diseases based on these new concepts.