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<title>Model Reference Description: Graphs</title>
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<h1 class="title">Model Reference Description: Graphs</h1>
<div id="a_0000000001" class="graph" style="background-color: #ffffff;">
<div class="graph-content">
<span class="source-link"><a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp-graphs.xml" title="Link to source XML code">&lt;source/&gt;</a></span><dl class="graph-header"><di><dt>Steady-state Gating Kinetics</dt><dd>Creator: <span class="vCard-N"><span class="vCard-Given">David</span> <span class="vCard-Family">Nickerson</span></span> <span class="vCard-EMAIL">(david.nickerson@nus.edu.sg)</span> <span class="vCard-Orgunit">Division of Bioengineering</span>, <span class="vCard-Orgname">National University of Singapore</span></dd><dd>Created: 2007-11-27</dd><dd>Publisher: Division of Bioengineering, National University of Singapore</dd></di></dl>
<div id="a_0000000001_image" class="graph-image">
  <a href="IKA_voltage_clamp_gates_SS.csv">
    <img alt="Graph output" title="Click for raw data"      src="IKA_voltage_clamp_gates_SS.png"/>
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<div id="a_0000000001_traces" class="traces">
<div id="a_0000000001_trace_000" class="trace" style="color: #ff0000">
<p id="a_0000000001_trace_000_label" class="trace-label">xA1_inf</p>
<dl class="trace-definition">
<dt id="a_0000000001_trace_000_x_title" class="graph-variable-title">x-axis</dt>
<dd id="a_0000000001_trace_000_x_simulation">Simulation:<a href="simulations.xml#a_0000000002"> <span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#simulation">...A-voltage-clamp.xml#simulation</span></a></dd>
<dd id="a_0000000001_trace_000_x_variable">Variable: <a href="a_0000000004.xml#a_0000000003"><span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#Vm">...ments/IKA-voltage-clamp.xml#Vm</span></a></dd>
<dt id="a_0000000001_trace_000_y_title" class="graph-variable-title">y-axis</dt>
<dd id="a_0000000001_trace_000_y_simulation">Simulation:<a href="simulations.xml#a_0000000002"> <span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#simulation">...A-voltage-clamp.xml#simulation</span></a></dd>
<dd id="a_0000000001_trace_000_y_variable">Variable: <a href="a_0000000004.xml#a_0000000005"><span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/components/IKA.xml#xA1_inf">...ist/components/IKA.xml#xA1_inf</span></a></dd>
<di id="a_0000000001_trace_000_experimental_data" class="trace-experimental-data"><dt>Experimental Data</dt><dd>
<dd><span class="source-link"><a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-activation.xml" title="Link to source XML code">&lt;source/&gt;</a></span></dd>
<dd>
<dl class="trace-experimental-data-metadata"><di><dt>&#x2715;</dt><dd>IKA steady state activation gating kinetics data from Amberg et al (2002).</dd><dd>Creator: <span class="vCard-N"><span class="vCard-Given">David</span> <span class="vCard-Family">Nickerson</span></span> <span class="vCard-EMAIL">(david.nickerson@nus.edu.sg)</span> <span class="vCard-Orgunit">Division of Bioengineering</span>, <span class="vCard-Orgname">National University of Singapore</span></dd><dd>Created: 2007-11-24</dd><dd>Pubmed reference: <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;cmd=Retrieve&amp;list_uids=12381815">12381815</a></dd><dd class="cmeta-bio_entity">Biological Entity: gastric antrum</dd><dd class="cmeta-species">Species: mouse</dd><dd class="external-resource-source">Data source: <a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-activation.csv">...ate-gating-data-activation.csv</a> <span title="data format">[text/csv; header=present]</span></dd><dd><dl class="cmeta-comment-list"><di class="cmeta-comment"><dt>Comment:</dt><dd class="cmeta-comment-value">Data used to fit the steady state activation gating kinetics of the IKA current in the Corrias &amp; Buist (2007) smooth muscle cellular electrophysiology model.</dd></di></dl></dd><dd><dl class="cmeta-modification-list"><di class="cmeta-modification"><dt>Modification [modified by <span class="vCard-FN">David Nickerson</span>]:</dt><dd class="cmeta-modification-value">Splitting the combined data into separate resources for ease of use.</dd><dd class="cmeta-modification-date">Modified: 2007-11-26</dd></di></dl></dd></di></dl>
</dd>
</dd>
</di>
</dl></div>
<div id="a_0000000001_trace_001" class="trace" style="color: #0000ff">
<p id="a_0000000001_trace_001_label" class="trace-label">xA2_inf</p>
<dl class="trace-definition">
<dt id="a_0000000001_trace_001_x_title" class="graph-variable-title">x-axis</dt>
<dd id="a_0000000001_trace_001_x_simulation">Simulation:<a href="simulations.xml#a_0000000002"> <span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#simulation">...A-voltage-clamp.xml#simulation</span></a></dd>
<dd id="a_0000000001_trace_001_x_variable">Variable: <a href="a_0000000004.xml#a_0000000003"><span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#Vm">...ments/IKA-voltage-clamp.xml#Vm</span></a></dd>
<dt id="a_0000000001_trace_001_y_title" class="graph-variable-title">y-axis</dt>
<dd id="a_0000000001_trace_001_y_simulation">Simulation:<a href="simulations.xml#a_0000000002"> <span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/experiments/IKA-voltage-clamp.xml#simulation">...A-voltage-clamp.xml#simulation</span></a></dd>
<dd id="a_0000000001_trace_001_y_variable">Variable: <a href="a_0000000004.xml#a_0000000006"><span title="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/components/IKA.xml#xA2_inf">...ist/components/IKA.xml#xA2_inf</span></a></dd>
<di id="a_0000000001_trace_001_experimental_data" class="trace-experimental-data"><dt>Experimental Data</dt><dd>
<dd><span class="source-link"><a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-inactivation.xml" title="Link to source XML code">&lt;source/&gt;</a></span></dd>
<dd>
<dl class="trace-experimental-data-metadata"><di><dt>&#x2715;</dt><dd>IKA steady state inactivation gating kinetics data from Amberg et al (2002).</dd><dd>Creator: <span class="vCard-N"><span class="vCard-Given">David</span> <span class="vCard-Family">Nickerson</span></span> <span class="vCard-EMAIL">(david.nickerson@nus.edu.sg)</span> <span class="vCard-Orgunit">Division of Bioengineering</span>, <span class="vCard-Orgname">National University of Singapore</span></dd><dd>Created: 2007-11-24</dd><dd>Pubmed reference: <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;cmd=Retrieve&amp;list_uids=12381815">12381815</a></dd><dd class="cmeta-bio_entity">Biological Entity: gastric antrum</dd><dd class="cmeta-species">Species: mouse</dd><dd class="external-resource-source">Data source: <a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-inactivation.csv">...e-gating-data-inactivation.csv</a> <span title="data format">[text/csv; header=present]</span></dd><dd><dl class="cmeta-comment-list"><di class="cmeta-comment"><dt>Comment:</dt><dd class="cmeta-comment-value">Data used to fit the steady state inactivation gating kinetics of the IKA current in the Corrias &amp; Buist (2007) smooth muscle cellular electrophysiology model.</dd></di></dl></dd><dd><dl class="cmeta-modification-list"><di class="cmeta-modification"><dt>Modification [modified by <span class="vCard-FN">David Nickerson</span>]:</dt><dd class="cmeta-modification-value">Splitting the combined data into separate resources for ease of use.</dd><dd class="cmeta-modification-date">Modified: 2007-11-26</dd></di></dl></dd></di></dl>
</dd>
</dd>
<dd>
<dd><span class="source-link"><a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-inactivation-smirnov.xml" title="Link to source XML code">&lt;source/&gt;</a></span></dd>
<dd>
<dl class="trace-experimental-data-metadata"><di><dt>&#x002B;</dt><dd>IKA steady state inactivation gating kinetics data from Smirnov et al (1992).</dd><dd>Creator: <span class="vCard-N"><span class="vCard-Given">David</span> <span class="vCard-Family">Nickerson</span></span> <span class="vCard-EMAIL">(david.nickerson@nus.edu.sg)</span> <span class="vCard-Orgunit">Division of Bioengineering</span>, <span class="vCard-Orgname">National University of Singapore</span></dd><dd>Created: 2007-11-28</dd><dd>Pubmed reference: <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;cmd=Retrieve&amp;list_uids=1474503">1474503</a></dd><dd class="cmeta-bio_entity">Biological Entity: ileum</dd><dd class="cmeta-species">Species: rat</dd><dd class="external-resource-source">Data source: <a href="http://www.bioeng.nus.edu.sg/compbiolab/p2/cellml/models/2007_corrias_buist/data/IKA-steady-state-gating-data-inactivation-smirnov.csv">...-data-inactivation-smirnov.csv</a> <span title="data format">[text/csv; header=present]</span></dd><dd><dl class="cmeta-comment-list"><di class="cmeta-comment"><dt>Comment:</dt><dd class="cmeta-comment-value">Data used to demonstrate the suitability of the steady state inactivation gating kinetics of the IKA current in the Corrias &amp; Buist (2007) smooth muscle cellular electrophysiology model.</dd></di></dl></dd></di></dl>
</dd>
</dd>
</di>
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<div class="footer">
 <span class="date-stamp">Created: 05:35:45 2008-02-05 (UTC) by <a href="http://cellml.sourceforge.net">CellMLSimulator</a></span>
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